世界卫生组织国际癌症研究机构致癌物清单(71页).doc

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1、-世界卫生组织国际癌症研究机构致癌物清单1类致癌物清单（116种）1类致癌物：对人类为确定致癌物。序号英文名称中文名称确定时间（年）1Acetaldehyde associated with consumption of alcoholic beverages随酒精饮料摄入的乙醛20122Acheson process, occupational exposure associated with艾其逊法(用焦炭和粘土混合加热制造石墨的工业方法)，职业暴露相关20173Acid mists, strong inorganic强无机酸雾20124Aflatoxins黄曲霉毒素20125Alcoho

2、lic beverages酒精饮料20126Aluminium production铝产品201274-Aminobiphenyl4-氨基联苯20128Areca nut槟榔果20129Aristolochic acid马兜铃酸201210Aristolochic acid, plants containing包含马兜铃酸的植物201211Arsenic and inorganic arsenic compounds砷和无机砷化合物201212Asbestos (all forms, including actinolite, amosite, anthophyllite, chrysotil

3、e, crocidolite, tremolite)铁石棉,石棉(各种形式,包括阳起石直闪石,温石棉,青石棉、透闪石)201213Auramine production金胺制造201214Azathioprine硫唑嘌呤201215Benzene苯201216Benzidine对二氨基联苯201217Benzidine, dyes metabolized to联苯胺、染料代谢201218Benzo a pyrene苯并芘201219Beryllium and beryllium compounds铍和铍化合物201220Betel quid with tobacco含烟草的槟榔嚼块201221

4、Betel quid without tobacco不含烟草的槟榔嚼块201222Bis(chloromethyl)ether; chloromethyl methyl ether (technical-grade)二氯甲基醚;一氯甲基醚(技术等级)201223Busulfan白消安2012241,3-Butadiene1,3-丁二烯201225Cadmium and cadmium compounds镉及镉化合物201226Chlorambucil苯丁酸氮芥201227Chlornaphazine萘氮芥201228Chromium (VI) compounds铬(VI)化合物201229Ci

5、closporin环孢素201230Clonorchis sinensis (infection with)华支睾吸虫(感染)201231Coal gasification煤的气化201232Coal, indoor emissions from household combustion of家庭燃烧的煤,室内排放201233Coal-tar distillation煤焦油蒸馏201234Coal-tar pitch煤焦油沥青201235Coke production焦炭制造201236Cyclophosphamide环磷酰胺201237Cyclosporine环孢霉素2012381,2-Di

6、chloropropane1,2-二氯丙烷201639Diethylstilbestrol己烯雌酚201240Engine exhaust, diesel发动机排放、柴油201341Epstein-Barr virus巴尔病毒201242Erionite毛沸石201243Estrogen therapy, postmenopausal雌激素治疗绝经后201244Estrogen-progestogen menopausal therapy (combined)雌激素-孕激素更年期治疗(联合)201245Estrogen-progestogen oral contraceptives (comb

7、ined)雌激素-孕激素口服避孕药(组合)201246Ethanol in alcoholic beverages酒精饮料中的乙醇201247Ethylene oxide环氧乙烷201248Etoposide依托泊苷201249Etoposide in combination with cisplatin and bleomycin依托泊苷结合顺铂和博来霉素201250Fission products, including strontium-90裂变产物,包括锶- 90201251Fluoro-edenite fibrous amphibole氟代-浅闪石纤维角闪石201752Formald

8、ehyde甲醛,福尔马林201253Haematite mining (underground)赤铁矿矿业(地下)201254Helicobacter pylori (infection with)幽门螺杆菌(感染)201255Hepatitis B virus (chronic infection with)乙型肝炎病毒(慢性感染)201256Hepatitis C virus (chronic infection with)丙型肝炎病毒(慢性感染)201257Human immunodeficiency virus type 1 (infection with)人类免疫缺陷病毒I型(感染)

9、201258Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59人类乳头瘤病毒类型16,18,31,33,35,39,45,51,52,56,58,59201259Human T-cell lymphotropic virus type I人类T淋巴细胞病毒I型201260Ionizing radiation (all types)电离辐射(所有类型)201261Iron and steel founding (occupational exposure during)钢铁铸造(职业暴露)201262

10、Isopropyl alcohol manufacture using strong acids使用强酸生产异丙醇201263Kaposi sarcoma herpesvirus卡波济肉瘤疱疹病毒201264Leather dust皮革尘埃201265Magenta production品红制造201266Melphalan美法仑201267Methoxsalen (8-methoxypsoralen) plus ultraviolet A radiation甲氧沙林甲氧补骨脂素花椒毒素+紫外线辐射201268Methyl-CCNU甲基环已亚硝脲2012694,4-Methylenebis(2

11、-chloroaniline) (MOCA)4,4-亚甲基(2-氯苯胺)201270Mineral oils, untreated or mildly treated矿物油,未经处理或温和治疗201271MOPP and other combined chemotherapy including alkylating agentsMOPP（氮芥、长春新碱、甲基苄肼、强的松）和其他联合化疗包括烷化剂2012722-Naphthylamine2-萘胺201273Neutron radiation中子辐射201274Nickel compounds镍化合物201275N-Nitrosonornico

12、tine (NNN) and 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)亚硝基降烟碱，亚硝胺201276Opisthorchis viverrini(infection with)泰国肝吸虫（麝猫后睾吸虫、香猫肝吸虫）(感染)201277Outdoor air pollution室外空气污染201678Outdoor air pollution, particulate matter in室外空气污染,颗粒物201679Painter (occupational exposure as a)画家(职业暴露)2012803,4,

13、5,3,4-Pentachlorobiphenyl (PCB-126)多氯联苯2012812,3,4,7,8-Pentachlorodibenzofuran多氯二苯并呋喃201282Phenacetin非那西汀201283Phenacetin, analgesic mixtures containing非那西汀,包含止痛剂混合物201284Phosphorus-32, as phosphate磷-32，磷酸201285Plutonium钚201286Polychlorinated biphenyls多氯联苯201687Polychlorinated biphenyls, dioxin-like

14、, with a Toxicity Equivalency Factor (TEF) according to WHO (PCBs 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189)类二恶英多氯联苯,毒性等价系数(TEF)取自WHO(多氯联苯77,77,81,77,81,123,126,156,157,167,169,189)201688Radioiodines, including iodine-131放射性碘,包括碘- 131201289Radionuclides, alpha-particle-emitting, inter

15、nally deposited放射性核素,粒子放射,内部沉积201290Radionuclides, beta-particle-emitting, internally deposited放射性核素,粒子放射,内部沉积201291Radium-224 and its decay products镭- 224及其衰变产物201292Radium-226 and its decay products镭- 226及其衰变产物201293Radium-228 and its decay products镭- 228及其衰变产物201294Radon-222 and its decay product

16、s氡- 222及其衰变产物201295Rubber manufacturing industry橡胶制造业201296Salted fish, Chinese-style中国式咸鱼201297Semustine 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, Methyl-CCNU司莫司丁(甲基环己亚硝脲)201298Shale oils页岩油201299Silica dust, crystalline, in the form of quartz or cristobalite二氧化硅粉尘、水晶、石英、方石英的形式2012100

17、Solar radiation太阳辐射2012101Soot (as found in occupational exposure of chimney sweeps)烟尘(发现于烟囱清洁工的职业暴露)2012102Sulfur mustard硫芥2012103Tamoxifen它莫西芬20121042,3,7,8-Tetrachlorodibenzo-para-dioxin四氯双苯环二噁英(TCDD)2012105Thiotepa三胺硫磷2012106Thorium-232 and its decay products钍- 232及其衰变产物2012107Tobacco smoke, sec

18、ond-hand吸二手烟2012108Tobacco smoking吸烟2012109Tobacco, smokeless无烟烟草2012110ortho-Toluidine邻甲苯胺2012111Treosulfan苏消安曲奥舒凡2012112Trichloroethylene三氯乙烯2014113Ultraviolet-emitting tanning devices紫外线放射日光浴设备2012114Vinyl chloride氯乙烯2012115Wood dust木粉2012116X- and Gamma-RadiationX、辐射20122类致癌物清单（共357种，含2A类71种，2B类

19、286种）2A类致癌物：对人类致癌性证据有限，对实验动物致癌性证据充分。2B类致癌物：对人类致癌性证据有限，对实验动物致癌性证据并不充分；或对人类致癌性证据不足，对实验动物致癌性证据充分。 序号英文名称中文名称确定时间（年）亚类11-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)1-（2-氯乙基）-3-环己基-1-亚硝基脲（CCNU）19872A21,2,3-Trichloropropane1,2,3-三氯丙烷19952A31,2-Dimethylhydrazine1,2-二甲基肼19992A41,3-Propane sultone1,3-丙

20、烷磺内酯20172A51-Nitropyrene1-硝基芘20142A62-Nitrotoluene2-硝基甲苯20132A74-Chloro-ortho-toluidine4-氯-邻-甲苯胺20102A85-Methoxypsoralen5-甲氧基补骨脂素19872A96-Nitrochrysene6-硝基屈,6-硝基联苯20142A10Acrylamide丙烯酰胺19942A11Adriamycin阿霉素19872A12alpha-Chlorinated toluenes (benzal chloride, benzotrichloride, benzyl chloride) and be

21、nzoyl chloride (combined exposures)-氯代甲苯（二氯甲基苯,三氯甲苯,氯化苄）和苯甲酰氯(混合暴露)19992A13Androgenic (anabolic) steroids雄激素（合成代谢）类固醇19872A14Art glass, glass containers and pressed ware (manufacture of)艺术玻璃,玻璃容器和压制品（制造）19932A15Azacitidine阿扎胞苷19902A16Biomass fuel (primarily wood), indoor emissions from household com

22、bustion of生物质燃料（主要是木材）,家用燃烧排放的废物20102A17Bischloroethyl nitrosourea (BCNU)双氯乙亚硝脲(卡氮芥)19872A18Bitumens, occupational exposure to oxidized bitumens and their emissions during roofing沥青,职业暴露于氧化沥青及其在屋顶过程中的排放20132A19Captafol敌菌丹19912A20Carbon electrode manufacture碳电极制造20102A21Chloral三氯乙醛20142A22Chloral hyd

23、rate水合氯醛20142A23Chloramphenicol氯霉素19902A24Chlorozotocin氯脲霉素19902A25Cisplatin顺铂19872A26Cobalt metal with tungsten carbide钴金属与碳化钨20062A27Creosotes杂酚油20102A28Cyclopentacdpyrene环戊二烯并 CD芘20102A29Diazinon二嗪磷20172A30Dibenza,hanthracene二苯并a,h蒽20102A31Dibenza,jacridine二苯并(a,j)丫啶20132A32Dibenzoa,lpyrene二苯并(a,

24、l)芘20102A33Dichloromethane (Methylene chloride)二氯甲烷20172A34Diethyl sulfate硫酸二乙酯19992A35Dimethyl sulfate硫酸二甲酯19992A36Dimethylcarbamoyl chloride二甲氨基甲酰氯19992A37Epichlorohydrin环氧氯丙烷19992A38Ethyl carbamate (Urethane)氨基甲酸乙酯（尿烷）20102A39Ethylene dibromide二溴乙烷19992A40Frying, emissions from high-temperature油炸

25、,高温排放20102A41Glycidol缩水甘油20002A42Glyphosate草甘膦20172A43Hairdresser or barber (occupational exposure as a)理发师或理发师（职业暴露）20102A44Human papillomavirus type 68人乳头瘤病毒68型20122A45Indium phosphide磷化铟20062A46IQ (2-Amino-3-methylimidazo4,5-fquinoline)IQ（2 -氨基-3 -甲基 4,5 - F 喹啉）19932A47Lead compounds, inorganic无机

26、铅化合物20062A48Malaria (caused by infection with Plasmodium falciparum in holoendemic areas)疟原虫（全地区感染的恶性疟原虫感染）20142A49Malathion马拉硫磷20172A50Merkel cell polyomavirus (MCV)默克尔细胞多瘤病毒（MCV）20142A51Methyl methanesulfonate甲磺酸甲酯19992A52N-Ethyl-N-nitrosoureaN-亚硝基-N-乙基脲19872A53Nitrate or nitrite (ingested) under

27、conditions that result in endogenous nitrosation硝酸盐或亚硝酸盐（摄入）,在导致内源性亚硝化的条件下20102A54Nitrogen mustard氮芥19872A55N-Methyl-N-nitrosoureaN-甲基-N-亚硝基脲19872A56N-NitrosodiethylamineN-亚硝基二乙胺19872A57N-NitrosodimethylamineN-二甲基亚硝胺19872A58Non-arsenical insecticides (occupational exposures in spraying and applicati

28、on of)非砷杀虫剂（喷洒和应用中的职业照射）19912A59Petroleum refining (occupational exposures in)石油炼制（职业暴露）19892A60Pioglitazone吡格列酮20162A61Polybrominated biphenyls多溴联苯20162A62Procarbazine hydrochloride盐酸甲基苄肼19872A63Shiftwork that involves circadian disruption涉及昼夜节律紊乱的转变20102A64Silicon carbide whiskers碳化硅晶须20172A65Styr

29、ene-7,8-oxide氧化苯乙烯19942A66Teniposide替尼泊苷20002A67Tetrachloroethylene (Perchloroethylene)四氯乙烯（全氯乙烯）20142A68Tetrafluoroethylene四氟乙烯20172A69Tris(2,3-dibromopropyl) phosphate磷酸三（2,3-二溴丙基）酯19992A70Vinyl bromide溴乙烯20082A71Vinyl fluoride氟乙烯20082A721,1,1,2-Tetrachloroethane1,1,2,2-四氯乙烷20142B731,1,2,2-Tetrach

30、loroethane四氯乙烷20142B741,1-Dimethylhydrazine1、1-二甲肼19992B751,2-Dibromo-3-chloropropane1,2-二溴-3-氯丙烷19992B761,2-Dichloroethane1,2-二氯乙烷19992B771,2-Diethylhydrazine1,2-二甲基肼19992B781,2-Epoxybutane1,2-环氧丁烷19992B791,3-Dichloro-2-propanol1,3-二氯-2-丙醇20132B801,3-Dichloropropene (technical-grade)1,3-二氯-1-丙烯 2-氯

31、丙烯基氯19992B811,3-Dinitropyrene1,3-二硝基芘20142B821,4-Dioxane1,4-二氧六环19992B831,6-Dinitropyrene1,6-二硝基芘20142B841,8-Dinitropyrene1,8-二硝基芘20142B851-(5-Nitrofurfurylidene)amino-2-imidazolidinone1-(5-硝基呋喃亚甲基)氨基-2-咪唑烷酮19872B861-Amino-2,4-dibromoanthraquinone1-氨基-2,4-二溴蒽醌20132B871-Chloro-2-methylpropene1-氯-2-甲基

32、-1-丙烯19952B881-Hydroxyanthraquinone1-羟基蒽醌20022B892-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole2-（2-甲酰肼基）-4-（5-硝基-2-呋喃基）噻唑19872B902,2-Bis(bromomethyl)propane-1,3-diol2,2-双(溴甲基)-1,3-丙二醇20002B912,3-Dibromopropan-1-ol2,3-二溴丙烷-1-ol20002B922,4-D (2,4-dichlorophenoxyacetic acid) (See also Chlorophenoxy

33、 herbicides)2,4-D（2,4-二氯苯氧乙酸）（参见氯苯除草剂）20162B932,4-Diaminoanisole2,4-二氨基苯甲醚硫酸盐20012B942,4-Diaminotoluene二氨基甲苯19872B952,4-Dinitrotoluene2,4-二硝基甲苯19962B962,4-Hexadienal2,4-己二烯醛20132B972,6-Dimethylaniline (2,6-Xylidine)2,6-二甲基苯胺（2,6-二甲代苯胺）19932B982,6-Dinitrotoluene2,6-二硝基甲苯19962B992-Amino-5-(5-nitro-2-f

34、uryl)-1,3,4-thiadiazole2-氨基-5-(5-硝基-2-呋喃)-1,3,4-噻二唑19872B1002-Methyl-1-nitroanthraquinone (uncertain purity)2-甲基-1-硝基蒽醌（不确定纯度）19872B1012-Methylaziridine (Propyleneimine)丙烯亚胺（亚胺）19992B1022-Methylimidazole2-甲基咪唑20132B1032-Nitroanisole2 -硝基苯甲醚19962B1042-Nitrofluorene2-硝基芴20142B1052-Nitropropane2-硝基丙烷19

35、992B1063-(N-Nitrosomethylamino)propionitrileN-亚硝基二正丙胺20042B1073,3-Dichloro-4,4-diaminodiphenyl ether3,3- 二氯-4,4-二氨基二苯醚19872B1083,3-Dichlorobenzidine3,3-二氯联苯胺19872B1093,3-Dimethoxybenzidine (ortho-Dianisidine)3,3-二甲基联苯胺（正-联茴香胺)19872B1103,3-Dimethylbenzidine (ortho-Tolidine)3,3-二甲基联苯胺（正-联甲苯胺)19872B111

36、3,7-Dinitrofluoranthene3,7-二硝基荧蒽20142B1123,9-Dinitrofluoranthene3,9-苯并荧蒽20142B1133-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone3-氯-4-(二氯甲基)-5-羟基-2(5H)-呋喃酮20042B1143-Monochloro-1,2-propanediol3 -氯- 1,2 -丙二醇20132B1153-Nitrobenzanthrone3-硝基苯并蒽酮20142B1164,4-Diaminodiphenyl ether4,4-二氨基二苯醚19872B117

37、4,4-Methylene bis(2-methylaniline)4,4-亚甲基双（2-甲基苯胺）19872B1184,4-Methylenedianiline4,4-二氨基二苯甲烷19872B1194,4-Thiodianiline4,4-硫代二苯胺19872B1204-Chloro-ortho-phenylenediamine4-氯- 邻苯二胺19872B1214-Methylimidazole4-甲基咪唑20132B1224-Nitropyrene4 -硝基芘20142B1234-Vinylcyclohexene4-乙烯基环己烯19942B1244-Vinylcyclohexene d

38、iepoxide4-乙烯基环己烯二环氧化物19942B1255-(Morpholinomethyl)-3-(5-nitrofurfurylidene)amino-2-oxazolidinone5-（吗啉代甲基）-3 - （5-硝基糠基）氨基 -2-恶唑烷酮19872B1265-Methylchrysene5-甲基屈20102B1275-Nitroacenaphthene5-硝基苊19872B1287H-Dibenzoc,gcarbazole7H-二苯并咔唑(194-59-2)20132B129A-alpha-C (2-Amino-9H-pyrido2,3-bindole)2-氨基-9H-吡啶2

39、,3-b吲哚19872B130Acetaldehyde乙醛19992B131Acetamide乙酰胺19992B132Acrylonitrile丙烯腈19992B133AF-2 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamideAF-2 2-（2-呋喃基）-3-（5-硝基-2-呋喃基）丙烯酰胺19872B134Aflatoxin M1黄曲霉毒素M119932B135Aloe vera, whole leaf extract芦荟全叶提取物20162B136a-Methylstyrenea-甲基苯乙烯20132B137Amsacrine安吖啶20002B138Ant

40、hraquinone蒽醌20132B139Antimony trioxide三氧化锑19892B140Aramite杀螟丹19872B141Auramine金胺20122B142Azaserine重氮丝氨酸19872B143Aziridine氮杂环丙烷19992B144Benzaanthracene苯并一蒽20102B145Benzjaceanthrylene苯并j乙烯合蒽20102B146Benzobfluoranthene苯并(b)荧蒽20102B147Benzocphenanthrene苯并- 3 ,4 -菲20102B148Benzojfluoranthene苯并j荧蒽20102B149Benzokfluoranthene苯并k荧蒽20102B150Benzofuran香豆酮19952B151Benzophenone苯甲酮20132B152Benzyl violet 4B苄基紫4B19872B153beta-Butyrolactone-丁内酯19992B154beta-Propiolactone-丙内酯19992B155Bitumens, occupational exposure to hard bitumens and their emissions during mastic asphalt work沥青,暴露于硬沥青及其排放物的工作者20132B15