各种实验动物权威麻醉用量.doc

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1、Four short words sum up what has lifted most successful individuals above the crowd: a little bit more.-author-date各种实验动物权威麻醉用量小鼠(mouse)麻醉劑量表小鼠(mouse)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC 1.2mg/kg IP鎮靜劑 Acepromazine 0.75mg/kg IM Diazepam 5mg/kg IP Ketamine 20mg/kg IM注射麻醉劑 Ketamine 22

2、-44mg/kg IM 100mg/kg IP 25mg/kg IV Pentobarbital 15mg/kg IV (以生理食鹽水10倍稀釋) 40-80mg/kg IP Thiopental 25mg/kg IV 50mg/kg IP Thiamylal 25-50mg/kg IV Tribromoethanol 0.2ml/10g IP (Avertin) (240mg/kg) (1.2 solution)混合注射麻醉劑 KetamineXylazine 50mg15mg/kg IM,IP 90-120mg10mg/kg IM,IP KetamineAcetylpromazine 10

3、0mg2.5mg/kg IM吸入麻醉劑 Carbon dioxide 50-70和氧混合 Inhalation Halothane 1-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-4 to effect Inhalation Methoxyflurane 0.5-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC 4mg/kg IP Butorphanol 1-5mg/kg q2-4h SC,IM Pentacozine 10mg/kg q2-4h SC,IM,IV不推薦使用的藥物

4、 Chloroform Ether Chloral Hydrate 370-400mg/kg IP Carbon tetrachloride Chlorpromazine Trichloroethylene TribromoethanolIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)大鼠(Rat)麻醉

5、劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC鎮靜劑 Acepromazine 5mg/kg IM,SC Diazepam 2.5mg/kg IP Xylazine 13mg/kg IM Ketamine 22mg/kg IM 20mg/kg IP注射麻醉劑 Ketamine 44mg/kg IM 40-160mg/kg IP 50mg/kg IV Fentanyl-droperidol 0.2-0.6ml/kg IP Pentobarbital 30-40mg/kg IV 30-50mg/kg IP Urethane 1000mg/kg

6、 IP混合注射麻醉劑 KetamineXylazine 40-80mg5-10mg/kg IM,IP KetaminePentobarbital 44mg25mg/kg (K)IM,(P)IP KetamineAcetylpromazine 75-80mg2.5mg/kg (K)IM,(A)IM吸入麻醉劑 Carbon dioxide 50-80和20-50氧混合 Inhalation Halothane 1-3 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-5 to effect Inhalation Methoxyflurane 1-3 to

7、effect Inhalation Enflurane 3-4 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chloroform Chloral Hydrate 300-450mg/kg IP Chlorpromazine Tribromoethanol 300mg/kg IPIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動

8、物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)沙鼠(Gerbil)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC鎮靜劑 Diazepam 5-10mg/kg IP Ketamine 22mg/kg IM注射麻醉劑 Ketamine 44mg/kg IMFentanyl-droperidol 0.15ml/kg IP Pentobarbital 30mg/kg I

9、V 60mg/kg IP,SC Tribromoethanol 0.2-0.25ml/10g IP (Avertin) (250-300mg/kg)混合注射麻醉劑 KetamineXylazine 50mg2mg/kg IP吸入麻醉劑 Halothane 1-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-4 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4

10、h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chloroform Ether AcepromazineIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)雪貂(ferret)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05mg/kg IV,IM,S

11、C鎮靜劑 Acepromazine 0.2-0.5mg/kg IM,SC Diazepam 2mg/kg IM Xylazine 1mg/kg IM,SC Ketamine 10mg/kg IM注射麻醉劑 Ketamine 30-60mg/kg IM Pentobarbital 30-36mg/kg IP Thiopental 60mg/kg IP混合注射麻醉劑 KetamineXylazine 10-25mg1-2mg/kg IM KetamineAcetylpromazine 20-35mg0.2-0.35mg/kg SC,IMKetamineDiazepam 25-35mg2-3mg/k

12、g IM吸入麻醉劑 Halothane 3-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 2-5 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation止痛劑 Meperidine 5-10mg/kg q2-4h IM,SC,IV Butorphanol 0.1-0.5mg/kg q12h IM Pentacozine 5-10mg/kg q4h IM不推薦使用的藥物 PentobarbitalIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入

13、Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)倉鼠(Hamster)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05-0.1mg/kg SC注射麻醉劑 Ketamine 200mg/kg IP Pentobarbital 70-90mg/kg IP Urethane 1500mg/kg IP混合注射麻醉劑 KetamineXylazine 80-100mg7-10mg/

14、kg IP KetamineDiazepam 40-100mg5mg/kg IP KetamineAcetylpromazine 150mg5mg/kg IM吸入麻醉劑 Halothane 1-4 to effect Inhalation Isoflurane 1-4 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chl

15、oral Hydrate 270-360mg/kg IP Fentanyl-droperidolIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)天竺鼠(Guinea Pig)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05-0.1mg/kg SC注射麻醉劑 Pentobarbital 25-35mg/kg IP Urethane 1500mg/

16、kg IV,IP混合注射麻醉劑 KetamineXylazine 40mg2mg/kg (K)IP,(X)IM KetamineDiazepam 20-30mg1-2mg/kg IM KetamineAcetylpromazine 25-55mg0.75-3mg/kg IM吸入麻醉劑 Halothane 0.5-4 to effect Inhalation Isoflurane 2-5 to effect Inhalation Methoxyflurane 0.5-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorpha

17、nol 2mg/kg q2-4h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chloral Hydrate 400mg/kg IP IM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)兔(Rabbit)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.2-0.3mg/kg IV,IM,SC鎮靜劑 Acepromazi

18、ne 0.5-2mg/kg IM Diazepam 1mg/kg IV 5-10mg/kg IM Xylazine 3mg/kg IV 4-6mg/kg IM Ketamine 22mg/kg IM注射麻醉劑 Ketamine 44mg/kg IM 15-20mg/kg IV Fentanyl-droperidol 0.15-0.44ml/kg IM Pentobarbital 30-50mg/kg IV,IP Thiopental(1) 15-30mg/kg IV Urethane 1000mg/kg IP,IV Thiamylal 25-30mg/kg IV混合注射麻醉劑 Ketamine

19、Xylazine 30-40mg3-5mg/kg IM 10mg/kg3mg/kg IV KetamineDiazepam 25mg5mg/kg IM KetamineAcetylpromazine 40mg0.5-1mg/kg IM吸入麻醉劑 Halothane 3-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 1.5-5 to effect Inhalation Methoxyflurane 0.5-3 to effect Inhalation Enflurane 3-4 to effect Inhalation止痛劑 Meperidine 5

20、-10mg/kg q2-3h IM,SC Butorphanol 0.1-0.5mg/kg q2-4h IM.IV,SC Pentacozine 5-10mg/kg q2-4h IV,IM Phenylbutazone 10mg/kg IV不推薦使用的藥物 Chloroform Chlorpromazine PromazineIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiew

21、icz Iowa State University Press1998)犬(Dog)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.03-0.1mg/kg IV,IM,SC鎮靜劑 Acepromazine 0.5-2mg/kg IM,IV,SC Diazepam 1-2.5mg/kg IV Xylazine 1mg/kg IV 1-4mg/kg IM Ketamine 5mg/kg IV 10mg/kg IM注射麻醉劑 Ketamine 20mg/kg IM 10mg/kg IV Fentanyl-droperidol 0.1-0.2ml/kg IM 0.05mg/kg IV

22、Pentobarbital 25-35mg/kg IV Thiopental(1) 20-30mg/kg IV Alpha-chloralose(1 solution) 40-100mg/kg IV Thiamylal 9-18mg/kg IV混合注射麻醉劑 KetamineXylazine 10mg2-4mg/kg IV(K),IM(X) KetamineDiazepam 7-10mg0.4mg/kg IV KetamineAcepromazine 10mg0.1mg/kg IV吸入麻醉劑 Halothane 3-4 to effect Inhalation 0.5-1.5(維持) Meth

23、oxyflurane 0.3-3 to effect Inhalation Enflurane 1-4 to effect Inhalation止痛劑 Meperidine 0.5-1mg/kg PO,IM,SC Butorphanol 1-2mg/kg IM.IV,SC Pentacozine 0.2mg/kg PO,IM Phenylbutazone 22mg/kg PO sid Xylazine 0.1mg/kg IM,IV bid Flunixin 1mg/kg IV sid不推薦使用的藥物 Alphaxalone-AlphadoleneIM：肌肉注射 IV：靜脈注射 SC：皮下注射

24、IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 靈長類(Primate)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.04-0.1mg/kg IV,IM,SC鎮靜劑 Acepromazine 0.25-1mg/kg IM,SC Diazepam 1mg/kg IM,IV Xylazine 0.5-2mg/kg IM Ketamine 7-14mg/kg IV 5-15mg/kg IM注射麻醉劑 Ketamine 5-40mg/kg IM 28-45mg/kg IV Fentanyl-droperidol 0.05-0.1ml/kg IM,IV Pentob